Human SIRP BETA 1 ELISA Kit (HUFI06511)

SIRP Beta 1 (SIRPB1) is a DAP12-associated transmembrane immunoreceptor expressed predominantly on myeloid lineage cells, including monocytes, macrophages, dendritic cells, and granulocytes. Unlike SIRP alpha, SIRPB1 does not engage CD47; instead it signals through the DAP12 adaptor to modulate innate immune cell activation, phagocytosis, and inflammatory cytokine production.

The Assay Genie SIRP Beta 1 ELISA Kit enables quantitative measurement of soluble SIRPB1 in research specimens, supporting investigations into neuroinflammation, Alzheimer's disease-associated microglial activation, osteoclastogenesis in rheumatoid arthritis, and tumor-associated macrophage biology.

Each kit supplies a pre-coated microplate, biotinylated detection antibody, streptavidin-enzyme conjugate, wash buffer, substrate solution, and stop reagent, sufficient for 96 determinations. Investigators tracking DAP12 pathway activity in cell culture experiments, primary tissue samples, and conditioned media rely on this reagent for soluble SIRPB1 quantification across immunology, cancer biology, and neurodegeneration studies.

For research use only; not for diagnostic or clinical procedures.