Human SIM2 ELISA Kit (HUFI06521)

SIM2 (Single-minded homolog 2) is a bHLH-PAS transcription factor encoded on chromosome 21q22.13 within the Down syndrome critical region, implicated in neurodevelopment, craniofacial morphogenesis, and aryl hydrocarbon receptor cross-talk. This Assay Genie kit enables quantitative measurement of SIM2 protein in human research samples via ELISA, supporting investigations into hypoxia signaling, neuronal differentiation, and trisomy 21 phenotype mechanisms. The kit is supplied as a complete set with pre-coated microplate, reference standards, biotinylated detection antibody, and chromogenic substrate sufficient for 96 individual reactions; store refrigerated and protect from light for optimal stability.