Human Sialin (SLC17A5) ELISA Kit

From Assay Genie, this sandwich ELISA kit is designed for the quantitative measurement of human sialin (SLC17A5) in human samples. The kit uses a colorimetric detection method and is reactive with human samples, including serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids.

The assay has a detection range of 0.156-10ng/mL with a sensitivity of 0.078ng/mL. Reported precision values include an intra-assay CV of 5.1% and an inter-assay CV of 9.6%. Specificity covers natural and recombinant human sialin. Sialin is encoded by the SLC17A5 gene and is involved in the transport of sialic acid across cell membranes; dysregulation of sialin function has been linked to genetic disorders such as Salla disease and sialic acid storage disease.

The kit is for research use only. Subcellular localisation of the target includes the cell membrane, cytoplasmic vesicles, secretory vesicles, synaptic vesicle membrane, and lysosome membrane, where it functions as a multi-pass membrane protein.