Human Sialic Acid Binding Ig Like Lectin 8 (SIGLEC8) ELISA Kit

The SIGLEC8 ELISA Kit from Assay Genie provides quantitative measurement of Siglec-8 protein in cell lysate samples using a microplate-based immunodetection workflow. Siglec-8 is a CD33-related sialic acid-binding lectin expressed selectively on eosinophils, mast cells, and basophils, where it acts as an inhibitory receptor that triggers eosinophil apoptosis and suppresses mast cell activation. Investigators studying allergic inflammation, bronchial asthma, eosinophilic esophagitis, chronic rhinosinusitis with nasal polyps, and hypereosinophilic syndrome use this assay to monitor Siglec-8 levels in cultured cells and primary immune cell lysates. The kit is intended for research use only, with reagents supplied in individual vials and components stored refrigerated to preserve antibody binding activity. Each kit contains pre-coated capture antibody, biotinylated detection reagent, recombinant protein standards, and TMB substrate required to generate a standard curve. This assay supports laboratory work exploring Siglec-8 as a therapeutic target in anti-eosinophil and anti-allergy drug discovery programs.