Human Sialic Acid Binding Ig Like Lectin 2 (SIGLEC2) ELISA Kit

Assay Genie's SIGLEC2 kit supports quantitative measurement of CD22, a 135 kDa B-cell restricted inhibitory receptor bearing immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Siglec-2 mediates B-cell receptor signaling thresholds and is implicated in lymphoma research, autoimmune disease models, and immune cell phenotyping studies.

The kit format includes a pre-coated well plate and reagents for in vitro quantitative analysis in a research use only workflow. Unused reagents should be stored at the temperatures noted in the enclosed manual, and reconstituted standards should be aliquoted and stored frozen to limit repeated freeze-thaw cycles.

Researchers characterize CD22 expression levels in disease versus healthy samples, supporting investigations into B-cell malignancies such as hairy cell leukemia and into novel antibody-drug conjugate development.