Human SHANK1 ELISA Kit (HUFI06538)

For researchers investigating synaptic function and neurodevelopmental disorders, the Assay Genie Human SHANK1 ELISA Kit provides quantitative measurement of SHANK1 (SH3 and multiple ankyrin repeat domains protein 1) in human research samples. SHANK1 is a scaffolding protein concentrated at the postsynaptic density of excitatory glutamatergic synapses, where it coordinates the assembly of receptor-associated signaling complexes that link NMDA and AMPA receptors to the actin cytoskeleton.

This kit is intended for research use only and fits into in vitro neuroscience, molecular biology, and cell biology workflows. Investigators focused on autism spectrum disorder, Phelan-McDermid syndrome (involving the 22q13.33 region), or related synaptic pathologies use Shank family protein measurements to complement genetic, behavioral, and pharmacological experiments.

The microplate-based workflow uses an absorbance readout compatible with standard laboratory plate readers, and each kit contains materials for 96 individual determinations. Reagents should be refrigerated upon arrival; refer to the enclosed datasheet for the precise storage temperature, reconstitution instructions, and full protocol steps before beginning the assay.