Human SH3GL2 ELISA Kit (HUFI06535)

Designed by Assay Genie for quantitative ELISA measurement of human SH3GL2 (also known as Endophilin A1), this immunoassay kit targets a BAR-domain and SH3-domain-containing accessory protein central to clathrin-mediated endocytosis at presynaptic terminals. SH3GL2 cooperates with dynamin and synaptojanin to drive membrane scission and uncoating during synaptic vesicle recycling, and altered expression has been documented in neurodegenerative disease research, particularly in studies of Alzheimer's disease pathology. The chromosomal locus at 9p22 has additionally been investigated as a candidate tumor suppressor region in oncology research.

Packaged in a 96 Assays kit format, the assay supports quantitative work in membrane trafficking, neuronal signaling, and biomarker discovery using human-derived biological research specimens. Researchers studying synaptic dysfunction, vesicle recycling defects, and neurological disease mechanisms will find this reagent relevant to their in vitro workflows.