Human sgp130 PharmaGenie ELISA Kit (SBRS1085)

The Human sgp130 PharmaGenie ELISA Kit from Assay Genie is a quantitative immunoassay developed to measure soluble gp130, the naturally secreted extracellular domain of the gp130 signal-transducing subunit that governs IL-6 family cytokine signaling through the JAK/STAT pathway. By selectively quantifying circulating sgp130 in human specimens, researchers can probe the IL-6 trans-signaling axis implicated in chronic inflammation, autoimmune conditions, cardiovascular pathology, and tumor progression. The reagent set uses a human-specific capture antibody pair, providing species-specific detection with no significant cross-reactivity to rodent gp130 homologs, and is supplied as a complete microplate-based format ready for in vitro laboratory work. Store the unopened kit refrigerated and protect from light to preserve antibody binding activity; bring all reagents to room temperature before running the assay. Each kit contains a pre-coated microplate, lyophilized recombinant sgp130 standards, biotinylated detection antibody, streptavidin-HRP conjugate, wash buffer, and substrate solution sufficient for running duplicate standard curves alongside unknown samples in support of biomarker validation, pharmacokinetic studies, and translational immunology research.