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Human SGEF ELISA Kit (HUFI08484)
  • Human SGEF ELISA Kit (HUFI08484)
Assay Genie

Human SGEF ELISA Kit (HUFI08484)

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HUFI08484

Price on request

Description

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The Human SGEF ELISA Kit from Assay Genie enables quantitative measurement of SGEF (also known as ARHGEF31 or H1fl), a Rho family guanine nucleotide exchange factor that activates RhoG signaling in endothelial and epithelial cells. SGEF contributes to cytoskeletal remodeling pathways that influence cell migration, junctional integrity, and angiogenic responses, and altered expression has been reported in studies of vascular barrier dysfunction, tumor cell motility, and inflammatory disease models. Researchers apply this immunoassay to investigate SGEF protein abundance in human samples for biomarker discovery and pathway-focused research. The antibody pair is calibrated for human-specific detection of SGEF, with no significant cross-reactivity reported against rat or mouse homologues under standard assay conditions. Reagents are supplied as a complete kit with a pre-coated microplate, matched antibody pair, recombinant standards, substrate solution, and wash buffers sufficient to process the full plate. Unopened components should be stored refrigerated and protected from light; reconstituted standards and detection antibody are best kept frozen in single-use aliquots to preserve activity across repeated freeze-thaw cycles.