Human Serpin B6 PharmaGenie ELISA Kit (SBRS1077)

The Assay Genie Serpin B6 immunoassay enables quantitative detection of human SERPINB6 protein in cell culture supernatant, plasma, or serum samples.

Serpin B6 is a clade B serpin that regulates intracellular serine proteases such as cathepsin G and kallikrein-related peptidases, with established roles in epithelial barrier maintenance and cochlear hair cell survival.

Published research links loss-of-function SERPINB6 mutations to autosomal recessive non-syndromic hearing loss (DFNB91), while expression studies have examined its dysregulation in keratinocyte inflammatory pathways and pancreatic beta-cell stress responses.

The kit format provides 96 individual determinations per plate, suitable for absorbance-based plate reader workflows in research use only settings.

Compatible downstream confirmatory methods include western blot and PCR-based transcript analysis of matched clinical or experimental samples.

Components should be refrigerated at 4 degrees C for short-term use and stored frozen at -20 degrees C for extended shelf life.