Human Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3) ELISA Kit

SPTLC3 is the long chain base subunit 3 of serine palmitoyltransferase, the enzyme that catalyzes the first, rate-limiting step in de novo sphingolipid biosynthesis. The SPTLC3 isoform modulates acyl-CoA substrate selectivity and influences ceramide chain length, and altered expression has been linked to metabolic dysregulation, insulin resistance, and certain cancer phenotypes. This Assay Genie kit employs a human-specific capture antibody for quantitative measurement of SPTLC3 protein levels in tissue homogenates, supporting research into sphingolipid metabolism, dermatology, and neurobiology. Unopened reagents should be stored at 4 °C and the microplate kept sealed in its foil pouch with desiccant. For research use only.