Human SERINC2 ELISA Kit (HUFI06603)

The Assay Genie SERINC2 quantitation kit provides researchers with a reliable in vitro tool for measuring serine incorporator 2 (SERINC2) protein levels in experimental samples. SERINC2 is a multi-pass transmembrane protein best known for its role as a restriction factor against HIV-1 and other retroviruses, where it impairs viral infectivity by being incorporated into budding virions. More broadly, SERINC2 contributes to membrane biosynthesis, phosphatidylserine regulation, and lipid remodeling, linking it to investigations in virology, immunology, neuroscience, and oncology.

Developed for cell biology and infectious disease research laboratories, the kit is supplied in a 96 Assays format with all reagents necessary to perform the immunoassay protocol. Each component is provided in individually sealed vials, and the included microplate is pre-configured to support reproducible standard curve generation across technical replicates. Reconstituted standards and prepared samples should be kept refrigerated at the temperature indicated on the lot certificate, and repeated freeze-thaw cycles of diluted conjugates should be avoided to preserve binding activity.

Typical applications include profiling endogenous SERINC2 expression in mammalian cell lines under viral infection, interferon, or cytokine stimulation; screening compound libraries for modulators of SERINC2 trafficking and surface presentation; and correlating SERINC2 abundance with disease phenotypes in translational studies of tumor progression or viral restriction mechanisms. The kit is intended for research use only and is not validated for diagnostic procedures. Refer to the lot-specific insert included in the box of components for run-specific instructions, dilution guidance, and lot traceability.