Human Semaphorin-7A (SEMA7A) ELISA Kit

From Assay Genie, this colorimetric sandwich ELISA kit is designed for the quantitative measurement of human Semaphorin-7A (SEMA7A) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. It detects natural and recombinant human Semaphorin-7A, with applications in studies of cell migration, immune response regulation, inflammation and related disease mechanisms.

The kit reports a sensitivity of 0.156 ng/mL and a detection range of 0.312-20 ng/mL. Intra-assay CV, inter-assay CV, linearity and recovery data are provided with the kit, and storage conditions are specified per component. The product is intended for research use only.

Semaphorin-7A is a GPI-anchored membrane glycoprotein (UniProt O75326) involved in integrin-mediated signalling, with reported roles in cell migration, immune cell activation, modulation of inflammation, T-cell-mediated immune responses, axon growth in the embryonic olfactory bulb, and dendrite outgrowth in melanocytes. Dysregulation has been linked to inflammatory disorders, autoimmune conditions and cancer, making it a focus of biomedical research into disease mechanisms and potential therapeutic targets.