Human Semaphorin-7A PharmaGenie ELISA Kit (SBRS1071)

Semaphorin-7A (SEMA7A, also known as CD108) is a GPI-anchored membrane protein implicated in immune cell signaling, axon guidance, and bone remodeling. Assay Genie's PharmaGenie ELISA kit provides quantitative measurement of human SEMA7A across cell culture supernatants, plasma, and serum samples, configured for 96 assays per kit to support biomarker and pathway research in immunology and oncology.

SEMA7A signals through integrin α1β1 and plexin C1, influencing T-cell activation, monocyte and macrophage polarization, and osteoclast differentiation. These roles make it a target of growing interest in studies of inflammatory disease, multiple sclerosis, and tumor microenvironment biology. The kit is supplied as a complete package containing pre-coated plate wells, recombinant protein standards, biotinylated detection antibody, streptavidin-HRP conjugate, and substrate solution, along with a step-by-step protocol covering standard curve preparation and recommended sample dilutions.

Intended for research use only, the kit accommodates standard laboratory plate readers for endpoint absorbance measurement and integrates with workflows that include conditioned media, patient biofluids, or tissue lysates. As part of the Assay Genie PharmaGenie portfolio, the product is backed by internal QC validation to help ensure reproducible lot-to-lot performance in studies where SEMA7A levels are correlated with disease states or therapeutic response.