Human Selenocysteine insertion sequence-binding protein 2-like (SECISBP2L) ELISA Kit

A high-quality sandwich ELISA from Assay Genie for quantitative detection of human Selenocysteine insertion sequence-binding protein 2-like (SECISBP2L). The kit is intended for research use only, reacts with human samples, and accepts serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. It is suited to research into selenocysteine biology, selenoprotein synthesis, and the role of SECISBP2L in disease pathogenesis.

According to the manufacturer, the assay has a detection range of 0.156–10 ng/mL and a sensitivity of 0.082 ng/mL. Intra-assay CV is 6.1% and inter-assay CV is 9.7%. Recovery is 103% (97–109%) in serum and 105% (99–111%) in plasma. Specificity covers natural and recombinant human SECISBP2L. The associated UniProt accession is Q93073 (NCBI Gene ID 9728), and listed synonyms include SECIS-binding protein 2-like and KIAA0256. SECISBP2L binds SECIS elements present on selenocysteine protein mRNAs but does not promote Sec incorporation into selenoproteins in vitro, and its dysregulation has been implicated in thyroid disorders, neurological conditions, and cancer.