Human Securin/PTTG1 ELISA Kit (HUFI06620)

PTTG1 (Pituitary Tumor-Transforming Gene 1) encodes securin, a regulatory protein that binds separase during mitosis and prevents premature chromosome separation. This Assay Genie ELISA kit enables quantitative detection of securin/PTTG1 in research specimens, supporting investigations into mitotic checkpoint control, sister chromatid cohesion, and tumorigenesis.

The product is validated specifically for human reactivity and is designated for research use only. Investigators studying pituitary adenomas, breast carcinoma, thyroid neoplasms, and colorectal cancer can use this kit to examine PTTG1 overexpression, which has been associated with tumor proliferation, invasion, and poor clinical prognosis.

Each kit ships with ready-to-use reagents, including a microplate pre-coated with capture antibody, and a complete protocol. The workflow produces a quantifiable signal on standard microplate absorbance readers, with results analyzable using common plate reader software. Researchers can apply the kit to cell culture supernatants, tissue homogenates, and experimental lysates to explore PTTG1 biology in cellular models and clinical sample cohorts.