Human SCMH1 ELISA Kit (HUFI06650)

The SCMH1 protein, also known as Sex Comb On Midleg Homolog 1, operates within Polycomb Repressive Complex 1 (PRC1), where it acts as an H3K27me3 reader that anchors long-term transcriptional silencing at developmental loci. In normal physiology SCMH1 supports stem cell renewal and germline integrity, while loss of function has been linked to hepatocellular carcinoma and breast cancer progression in published tumor biology studies. Quantifying SCMH1 abundance in these settings helps researchers connect chromatin-state dynamics to disease phenotypes.

This Assay Genie kit is supplied as a 96 Assays microplate configuration with pre-coated wells that capture recombinant and native human SCMH1 from prepared extracts. The format is commonly paired with western blot, qPCR, and chromatin immunoprecipitation to layer protein-level abundance on top of mRNA and ChIP-seq observations from matched cohorts. Reagents are stored at 4 °C between uses; freeze-thaw cycles are minimized and the standard curve materials are aliquoted on first thaw. The product is intended for research use only and supports in vitro applications including cell line analyses, primary tissue preparations, and ex vivo treatment comparisons.