Human SARS2 (Serine-tRNA ligase, mitochondrial ) ELISA Kit (HUFI06666)

Mitochondrial seryl-tRNA synthetase, encoded by the SARS2 gene, attaches serine to its cognate mitochondrial tRNAs during organellar translation, and biallelic variants in this gene have been linked to progressive microcephaly, seizures, and intellectual disability. This Assay Genie ELISA kit provides a colorimetric, microplate-based immunoassay for quantitative measurement of human SARS2 protein, with reagents supplied for 96 determinations. The product is configured for laboratory research use only and is intended for studies of mitochondrial translation, oxidative phosphorylation defects, and the molecular characterization of aminoacyl-tRNA synthetase disorders. Reconstituted standards and detection antibodies should be kept refrigerated between runs, and the supplied components arrive in sealed vials and bottles suitable for repeated short-term access. Researchers investigating mitochondrial disease mechanisms, including those working with patient-derived lymphoblasts, fibroblasts, or other human cellular models, can apply the kit to monitor expression changes and validate variant effects at the protein level. Each kit includes a pre-coated plate, lyophilized standards, biotinylated detection reagent, wash buffer, and substrate solution in quantities sufficient to complete a full ninety-six-determination run with appropriate replicates.