Human Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (ATP2A3) ELISA Kit

This Sandwich ELISA kit from Assay Genie is intended for the detection of human Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (ATP2A3) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay uses a colorimetric detection method. ATP2A3, also referred to as Calcium pump 3 and SERCA3, is a magnesium-dependent enzyme that catalyses the hydrolysis of ATP coupled with the transport of calcium from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen, contributing to calcium sequestration involved in muscular excitation and contraction.

According to the manufacturer's specifications, the assay has a detection range of 0.312-20ng/ml and a sensitivity of 0.19ng/mL. Reported precision values include an Intra CV of 5.3% and an Inter CV of 9.5%. The kit is specific for natural and recombinant human ATP2A3, is for research use only, and is intended for neuroscience research. Dysregulation of ATP2A3 has been linked to muscle disorders, heart conditions, and neurological disorders, making the measurement of ATP2A3 levels relevant to studies of calcium ion transport in cells.