Human Ryanodine receptor 2/RYR2 ELISA Kit

Manufactured by Assay Genie, this sandwich ELISA kit is designed for the quantitative measurement of Ryanodine Receptor 2 (RYR2) levels in human samples. It is a double-antibody sandwich ELISA with a colorimetric detection method, offering a sensitivity of 0.375 ng/mL and a working range of 0.625–40 ng/mL. The kit is validated for use with serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples, and should be stored at 2–8°C for 12 months.

RYR2 is a critical component of calcium release in muscle cells and plays a key role in muscle contraction. Mutations in the RYR2 gene have been linked to conditions such as arrhythmias and heart failure, making this kit a useful tool for research into cardiac function and muscle physiology, providing insights into the role of RYR2 in health and disease.

Performance characteristics include linearity of 88–101% for serum, 82–97% for EDTA plasma, and 85–94% for heparin plasma at the 1:2 dilution, with recovery rates averaging 96% for serum, 98% for EDTA plasma, and 95% for heparin plasma.