Human Ryanodine Receptor 2, Cardiac (RYR2) ELISA Kit

Cardiac researchers investigating calcium handling in cardiomyocytes can use this Assay Genie kit to measure Ryanodine Receptor 2 levels in human heart tissue preparations. RYR2 is the principal intracellular calcium release channel of the sarcoplasmic reticulum in cardiac muscle, where it mediates calcium-induced calcium release during excitation-contraction coupling. The kit supports studies of inherited arrhythmia syndromes linked to RYR2 dysfunction, including catecholaminergic polymorphic ventricular tachycardia (CPVT) and arrhythmogenic right ventricular cardiomyopathy type 2 (ARVC2), as well as investigations of altered calcium handling in heart failure and drug-induced cardiotoxicity screening. Store reconstituted reagents refrigerated and use the 96 determinations per kit for medium-throughput screening of patient-derived or model-system samples. For research use only.