Human RUNX1T1 (RUNX1 translocation partner 1) ELISA Kit (HUFI06683)

The Assay Genie quantitative immunoassay kit measures human RUNX1 translocation partner 1 (RUNX1T1) protein concentrations using an ELISA workflow, supporting investigations into acute myeloid leukemia biology and related hematologic research. RUNX1T1, also called ETO or MTG8, is involved in the t(8;21)(q22;q22) chromosomal translocation that fuses RUNX1 and RUNX1T1 into the AML1-ETO oncogene, one of the most recurrent cytogenetic abnormalities in AML. Quantifying RUNX1T1 expression aids studies of leukemogenesis, minimal residual disease monitoring, and transcriptional co-repressor complex function. Each kit is supplied as a 96 Assays package configured for absorbance-based readouts with sample matrices derived from human blood, evaluated in a research-use-only workflow. Unopened reagents should be kept refrigerated until first use to preserve antibody binding activity; long-term storage of unused strips should follow the kit insert. The 96 Assays format provides sufficient microplate wells, standards, and detection reagents to run standard curves alongside replicate sample determinations. Beyond AML research, the assay supports investigation of normal RUNX1T1 functions in neuronal differentiation and adipogenesis, broadening its utility across cell biology and oncology laboratories.