Human Runt-related transcription factor 2 (RUNX2) ELISA Kit

Designed for the accurate measurement of Human Runt-related transcription factor 2 (RUNX2) levels, this Sandwich ELISA Kit from Assay Genie is validated for use with human samples including serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. RUNX2 is a key transcription factor involved in osteoblastic differentiation and skeletal morphogenesis, with dysregulation linked to conditions such as osteoporosis, osteosarcoma, and craniosynostosis, making it an important biomarker in bone-related research.

The assay uses a colorimetric detection method and provides a detection range of 0.312–20 ng/mL with a sensitivity of 0.056 ng/mL. Intra-assay CV is 4.7% and inter-assay CV is 6.6%. The kit is specific for natural and recombinant human RUNX2 (UniProt Q13950), which is localised to the nucleus, and is intended for research use only in the cancer research area.

Synonyms for the target include AML3, CBFA1, OSF2, and PEBP2A. Recovery and linearity performance data are supplied with the kit to support reliable quantification in serum, EDTA plasma, and heparin plasma samples.