Human Runt Related Transcription Factor 2 (RUNX2) ELISA Kit

A core regulator of osteoblast differentiation, RUNX2 is a runt-domain transcription factor that drives bone matrix gene expression and skeletal mineralization. This Assay Genie ELISA kit enables quantitative measurement of RUNX2 protein in human samples, supporting research in bone biology, orthopedics, craniofacial development, and dental science. The assay accepts tissue homogenates and cell lysates, uses a colorimetric method, and is configured for 96 assays per kit.

Each kit includes pre-coated microplate wells, biotinylated detection antibody, standards, and the buffers required to run the full plate. Researchers commonly use this type of assay to monitor osteogenic differentiation of mesenchymal stem cells, compare RUNX2 levels across osteosarcoma and other bone-related cell models, and investigate conditions such as cleidocranial dysplasia, in which RUNX2 haploinsufficiency has been documented. Reagents are supplied in single-use vials, and the workflow is compatible with standard plate readers and standard incubation equipment. For research use only.