Human RNF8 ELISA Kit (HUFI06787)

Engineered for quantitative measurement of RING finger protein 8 in human specimens, this ELISA-format immunoassay from Assay Genie supports investigation of DNA damage response signaling. RNF8 acts as an E3 ubiquitin ligase responsible for histone H2A ubiquitination at double-strand break sites, an early chromatin modification that recruits downstream repair effectors including 53BP1 and BRCA1 to damaged chromatin.

Packaged as a 96 Assays kit, the format suits research programs in cancer biology, genotoxic stress, and cell cycle checkpoint regulation. Investigators studying radiation-induced DNA damage, chemotherapeutic agent mechanisms, or hereditary repair deficiencies can apply the kit to monitor RNF8 protein expression in patient-derived liquid specimens. Each kit supplies the pre-coated plate, lyophilized standards, biotinylated detection antibody, streptavidin-HRP conjugate, wash buffer, and TMB substrate required to run the full protocol.

The colorimetric endpoint is read on standard microplate absorbance instruments, eliminating the need for specialized hardware. With human-specific reactivity, results translate directly to clinical and translational research workflows. Reagents should be stored refrigerated to preserve activity through the stated shelf life.