Human RNF6 ELISA Kit (HUFI06786)

This Assay Genie kit enables quantitative measurement of RNF6, an E3 ubiquitin ligase first characterized for its role in polyubiquitinating the androgen receptor and modulating its transcriptional activity in prostate cancer cells. Subsequent studies have shown RNF6 contributes to polyubiquitylation of SHP-1 phosphatase, influences Wnt/beta-catenin pathway output, and regulates skeletal myogenesis through targeted protein degradation. The microplate-based assay supports a standard detection range of 0.156–10 ng/mL and is intended for comparing RNF6 expression across patient cohorts, tumor biopsy homogenates, and cultured cell samples. Researchers investigating ubiquitylation-mediated regulatory mechanisms, drug resistance in androgen-driven cancers, and muscle satellite cell differentiation find this kit useful for biomarker tracking and pathway-focused studies in vitro.