Human RLBP1 ELISA Kit (HUFI06807)

Retinaldehyde-Binding Protein 1 (RLBP1), also called CRALBP, is a 36 kDa visual-cycle carrier that shuttles 11-cis-retinol and 11-cis-retinaldehyde between photoreceptors and the retinal pigment epithelium. Mutations in the gene encoding RLBP1 cause autosomal recessive retinitis pigmentosa, Leber congenital amaurosis, and Bothnia retinal dystrophy, so quantitative measurement of this protein is valuable for ophthalmology and inherited retinal disease research. The Assay Genie Human RLBP1 ELISA Kit provides a 96 Assays configuration built around an ELISA immunoassay format, giving laboratories a tool to probe circulating RLBP1 levels in patient samples and experimental model systems.

Typical use cases include biomarker discovery in retinal degeneration cohorts, mechanistic studies of the visual cycle in RPE cell culture models, and translational research linking CRALBP expression to disease severity in autosomal recessive retinal dystrophies. Researchers investigating photoreceptor outer-segment recycling, RPE physiology, and genotype-phenotype correlations in CRALBP-deficient families can incorporate this kit into case-control panels, time-course analyses, and drug-response studies aimed at slowing or preventing vision loss.