Human Ribonuclease L (RNASEL) ELISA Kit

Quantitative measurement of Ribonuclease L protein in human research specimens is supported by the Assay Genie RNASEL ELISA Kit, a microplate-based immunoassay configured for high-throughput workflows. RNASEL is a constitutively expressed endoribonuclease that is strongly upregulated by interferon signaling and serves as a central effector of the innate antiviral response, where it degrades viral and cellular single-stranded RNA. The kit is commonly used to evaluate RNASEL protein levels in studies of interferon pathway activation, viral infection models, prostate cancer susceptibility genetics, and inflammatory disease mechanisms across serum specimens, plasma specimens, and tissue homogenate preparations from human donors.

Reagents supplied in the kit support the full assay workflow on a standard microplate reader, with results read as optical density values that researchers correlate against a calibrated standard curve. The product is intended for research use only and is configured for use with human-derived samples, providing a reproducible tool for laboratories studying host defense pathways.