Human RHEB (Ras homolog enriched in brain) ELISA Kit (HUFI06831)

The Assay Genie Human RHEB ELISA Kit provides researchers with a quantitative tool to measure Ras homolog enriched in brain, a small GTPase that acts as an upstream activator of the mTORC1 complex and a central regulator of cell growth, protein synthesis, and autophagy.

RHEB sits at the crossroads of nutrient sensing and oncogenic signaling, cycling between active GTP-bound and inactive GDP-bound conformations. Dysregulated RHEB activity has been implicated in tuberous sclerosis complex, neurodegenerative disease models, and multiple cancer contexts, making accurate quantitation of the protein relevant to pathway-focused studies in signal transduction, tumor biology, and neuroscience research.

The kit is intended for research use only and supports in vitro workflows in academic and translational laboratories studying Ras superfamily GTPases, insulin and amino acid signaling, and downstream effectors including S6K1 and 4E-BP1 phosphorylation. Pairing ELISA readouts with complementary methods such as western blot or immunoprecipitation allows cross-validation of expression changes across biological samples.

Each kit provides reagents sufficient for 96 assays in a microplate format, packaged for standard laboratory handling.