Human RFC1 (Reduced Folate Carrier 1) ELISA Kit (HUFI04748)

Encoded by the SLC19A1 gene, the Reduced Folate Carrier 1 (RFC1) is a 12-transmembrane domain transporter that mediates cellular uptake of reduced folates such as 5-methyltetrahydrofolate and antifolate therapeutics including methotrexate. Studies on RFC1 expression are central to understanding antifolate drug resistance in leukemia and lymphoma, methotrexate response in rheumatoid arthritis, placental folate transport, and inherited folate malabsorption syndromes. This quantitative ELISA kit from Assay Genie is supplied in a 96 Assays microplate configuration intended for research use only, supporting laboratory work in oncology, hematology, and folate metabolism applications.