Human Retinol Binding Protein 3, Interstitial (RBP3) ELISA Kit

Retinoid transport between the retinal pigment epithelium and photoreceptor cells depends on Interphotoreceptor Retinoid-Binding Protein, also called IRBP or Retinol Binding Protein 3 (RBP3), a large glycoprotein secreted by photoreceptors of the retina and by the pineal gland. This carrier protein moves vitamin A derivatives such as all-trans retinol through the interphotoreceptor matrix, sustaining the visual cycle that regenerates the chromophore used in phototransduction. The Assay Genie human RBP3 ELISA Kit is built for quantitative measurement of native RBP3 in research samples, and is validated for use with tissue homogenates and cell lysates prepared from ocular and neural tissue. Vision scientists working on retinitis pigmentosa, age-related macular degeneration, diabetic retinopathy, Leber congenital amaurosis, and related photoreceptor-degeneration disorders apply this kit to profile RBP3 expression in patient-derived samples and in animal or cell-based disease models. Each kit ships with all required reagents, calibrated standards, and a microplate pre-configured for 96 assays; unopened kit components should be refrigerated upon arrival, and reconstituted standards should be aliquoted and frozen to limit repeated freeze-thaw cycles. For research use only; not intended for diagnostic procedures.