Human Retinoic acid receptor responder protein 2 (RARRES2) ELISA Kit

Assay Genie's Sandwich ELISA kit is designed for the precise measurement of Retinoic acid receptor responder protein 2 (RARRES2), also known as Chemerin, in human samples such as serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. RARRES2 is described as a key protein involved in immune response regulation, inflammation, and metabolism, with its dysregulation linked to obesity, diabetes, and inflammatory conditions, making it a potential biomarker for research in these areas.

The assay operates with a detection range of 0.156-10ng/mL and a sensitivity of 0.045ng/mL. Reported precision includes an Intra CV of 5.6% and an Inter CV of 10.2%. Linearity has been validated in serum, EDTA plasma, and heparin plasma at dilutions of 1:2, 1:4, 1:8, and 1:16. Recovery for serum averages 114% (range 108-120%), and plasma averages 116% (range 110-120%).

Specificity covers natural and recombinant human RARRES2, with the listed research area being cardiovascular. The target protein functions as an adipocyte-secreted adipokine regulating adipogenesis, metabolism, and inflammation via activation of the chemokine-like receptor 1 (CMKLR1), with additional ligands including GPR1 and CCRL2. UniProt entry: Q99969. For research use only.