Human RERE (Arginine-glutamic acid dipeptide repeats protein) ELISA KIT (HUFI05444)

This 96 Assays ELISA kit from Assay Genie enables quantitative measurement of arginine-glutamic acid dipeptide repeats protein (RERE), a nuclear receptor corepressor involved in transcriptional regulation, chromatin remodeling, and embryonic patterning. RERE, also designated ATN1L or ATROPHIN-2, contains a characteristic arginine-glutamic acid dipeptide repeat domain and functions as a scaffold for histone deacetylase recruitment and Wnt/β-catenin signaling modulation.

Mutations and copy-number variations affecting the RERE gene are linked to RERE-related neurodevelopmental disorder (1p36 deletion spectrum), characterized by intellectual disability, cardiac anomalies, and renal malformations. The protein has also been characterized as a tumor suppressor whose loss of function contributes to clear cell renal cell carcinoma progression and other malignancies.

The kit includes a pre-coated microplate, detection antibody, standard diluent, wash buffer, substrate, and stop solution sufficient to perform quantitative ELISA workflows in a research laboratory setting. Application areas include studies of chromatin remodeling complexes, neurodegenerative disease mechanisms, renal carcinoma cell signaling, and developmental biology. Reagents should be stored refrigerated between uses per the package insert to preserve activity.