Human Renin receptor (ATP6AP2) ELISA Kit

A sandwich ELISA from Assay Genie for the quantitative detection of the human Renin receptor (ATP6AP2). The renin receptor functions as a renin and prorenin cellular receptor and plays a role in the renin-angiotensin system (RAS), which is involved in blood pressure regulation and fluid balance. The assay is reactive with human samples and is intended for research use only.

Compatible sample types include serum, plasma, cell culture supernates, cell or tissue lysates, tissue homogenates and other biological fluids. Detection is colorimetric, and the kit detects both natural and recombinant human Renin receptor. Performance characteristics stated on the product datasheet include a sensitivity of 0.12 ng/mL and a detection range of 0.312–20 ng/mL, with an intra-assay CV of 5.8% and an inter-assay CV of 8.7%.

Linearity was tested across serum, EDTA plasma and heparin plasma at dilutions of 1:2, 1:4, 1:8 and 1:16 (n = 5). Recovery averaged 109% in serum (range 103–115%) and 111% in plasma (range 105–117%). The kit supports research into renin-angiotensin biology and its implications in cardiovascular health.