Human REL (Proto-oncogene c-Rel) ELISA Kit (HUFI04944)

Quantitative measurement of the human proto-oncogene c-Rel transcription factor is supported by this immunoassay kit from Assay Genie, intended for research use only in vitro investigation of NF-κB family signaling. The c-Rel protein, a member of the Rel/NF-κB transcription factor family, plays pivotal roles in lymphocyte proliferation, immune cell differentiation, and inflammatory gene regulation. Aberrant c-Rel activity has been implicated in lymphoid malignancies and autoimmune disorders, making it a target of interest in oncology and immunology laboratories.

The assay accommodates standard human biofluid specimens, with a 96 Assays configuration supporting medium-throughput screening studies. Investigators can apply the kit to studies exploring transcriptional regulation, B-cell receptor signaling pathways, and chemoresistance mechanisms in lymphoma cell lines. Components require refrigerated storage to preserve antibody binding activity and reagent stability across multiple experimental runs.

Each kit enables detection of endogenous c-Rel levels in human-derived specimens, providing a tool for studies of NF-κB pathway activation under various stimulation conditions. The assay is compatible with standard microplate readers and supports laboratory research applications investigating immune signaling cascades and oncogenic transcription factor expression.