Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

Quantitative matched-antibody immunoassay from Assay Genie for measuring human RANK (Receptor Activator of Nuclear factor Kappa-B, TNFRSF11A) in tissue homogenates and cell lysates. The receptor is a Type I transmembrane member of the TNF receptor superfamily and serves as the cell-surface signaling receptor for RANKL (TNFSF11/TRANCE), driving osteoclast differentiation, bone resorption, and dendritic cell survival. Investigators studying bone metabolism, osteoporosis, rheumatoid arthritis, periodontal disease, bone metastasis, and osteoimmunology rely on this 96-assay kit for in vitro research quantifying receptor levels in cell and tissue-derived samples. Reagents are supplied for use in a Colorimetric microplate workflow with ready-to-use and concentrated components, and should be stored refrigerated between uses to protect antibody binding activity. RANK quantification supports work on the RANK/RANKL/OPG axis, a central regulatory triad in skeletal homeostasis and immune cell signaling.