Human Ras Homolog Gene Family, Member A (RHOA) ELISA Kit

This colorimetric ELISA Kit from Assay Genie provides quantitative measurement of Ras Homolog Gene Family Member A (RHOA) protein in human research specimens. RHOA is a ~21 kDa small GTPase that acts as a molecular switch in actin cytoskeleton remodeling, regulating stress fiber formation, focal adhesion assembly, cell migration, and signal transduction downstream of Rho-associated kinase.

The kit is validated for use with tissue homogenates, cell lysates, and prepared biological research specimens, supporting in vitro studies of cytoskeletal dynamics, tumor cell invasion, endothelial permeability, and immune cell signaling. Sufficient reagents are included for 96 determinations on a standard microplate, and the assay is intended for research use only.

RHOA dysregulation is implicated in cancer metastasis, cardiovascular remodeling, and inflammatory disease research, making accurate quantification valuable for laboratories studying Rho/ROCK pathway activity, GTPase cycling, and downstream effectors such as ROCK1, mDia, and LIM kinase. Components are shipped refrigerated; store according to the supplied insert to preserve antibody binding activity across the full assay run.