Human RAMP1 (Receptor activity-modifying protein 1) ELISA Kit (HUFI08029)

Quantifying Receptor activity-modifying protein 1 in human specimens, this Assay Genie ELISA Kit delivers a colorimetric microplate readout suitable for CGRP receptor signaling studies, migraine research workflows, and cardiovascular signaling investigations.

RAMP1 is a single-pass transmembrane accessory protein that chaperones the calcitonin receptor-like receptor (CLR) to the cell surface and dictates ligand selectivity at the resulting receptor complex. Measuring circulating or tissue-derived RAMP1 helps researchers map how accessory proteins shape GPCR pharmacology outcomes in vitro and in vivo, including AM1 receptor pharmacology, AMY1 receptor composition, and CGRP-responsive cell models.

The kit ships in a 96 Assays format with pre-coated wells, matched capture and detection antibodies, recombinant standards, and assay buffers required for a complete quantitative workflow. Researchers typically pair this RAMP1 measurement with CLR expression data, downstream cAMP signaling assays, or receptor internalization studies to dissect how accessory protein expression modulates receptor trafficking and ligand-driven signaling.

Components should be stored refrigerated upon arrival and the chromogenic substrate protected from light until use. Each kit is intended for research use only in laboratory settings and is not validated for diagnostic procedures.