Human RALGPS1 (Ras-specific guanine nucleotide-releasing factor RalGPS1) ELISA KIT (HUFI04925)

RalGPS1 Signaling Biology: RALGPS1 operates as a Ras-dependent guanine nucleotide exchange factor that selectively activates RalA and RalB small GTPases, bridging classical Ras signaling with Ral-driven pathways controlling vesicle trafficking, exocytosis, and cytoskeletal dynamics.

Research Applications: Investigators probing oncogenic Ras-Ral cascades, exosome biogenesis, or membrane trafficking use this quantitative immunoassay from Assay Genie to monitor endogenous RALGPS1 abundance in clinical and experimental specimens, with a working detection range of 0.156–10 ng/mL and demonstrated cross-reactivity with human and mouse RALGPS1. The platform supports studies of cancer cell proliferation, metastatic dissemination, and Ral-mediated secretory processes in Ras-mutated tumors.

Kit Components: Each package contains a pre-coated microwell plate, capture and detection antibodies, recombinant protein standards, and assay buffers sufficient to generate a standard curve. Reagents are optimized for reproducibility across replicate wells, supporting quantitative comparison between cohorts.