Human RAF1 ELISA Kit (HUFI08572)

Raf-1 kinase is a serine/threonine protein kinase that serves as the principal MAP3K in the canonical RAS-RAF-MEK-ERK signal transduction cascade, operating downstream of activated RAS GTPases and upstream of MEK1/2. The Assay Genie Human RAF1 ELISA Kit provides a quantitative immunoassay for measuring Raf-1 levels in research samples, supporting investigations of the MAPK signaling pathway that governs proliferation, differentiation, and apoptosis across multiple cell types.

Applications include signal transduction studies, oncology research, drug response work, and biomarker discovery programs. Documented RAF1 mutations have been linked to Noonan syndrome, LEOPARD syndrome, and several malignancies, making Raf-1 protein quantification relevant for translational research into pathway dysregulation and targeted therapeutics.

This 96 Assays format kit is supplied in a box and should be stored refrigerated until first use. All components are intended for in vitro research use only and have not been validated for clinical diagnostic procedures.