Human RAD23 Homolog B (RAD23B) ELISA Kit

The RAD23B protein functions as a key component of the nucleotide excision repair pathway, where it recognizes bulky DNA lesions and helps recruit the XPC-RAD23B-CEN2 complex to damaged chromatin. Beyond its canonical role in NER, RAD23B carries ubiquitin-associated (UBA) domains that shuttle ubiquitinated substrates toward the proteasome, coupling DNA repair to protein turnover and ER-associated degradation.

This quantitative immunoassay from Assay Genie supports research into xeroderma pigmentosum, cancer biology, neurodegeneration, and chemotherapeutic resistance. Investigators working on DNA damage response, ubiquitin signaling, and genome stability can use the kit to quantify RAD23B levels in cell lysates and tissue homogenates derived from human samples.

The kit is intended for research use only and delivers reproducible optical density readings across a standard microplate format, making it well matched to batch processing in shared core laboratories. Store reagents as specified in the package insert and protect components from light to preserve assay performance across runs. For in vitro characterization of DNA repair pathways and ubiquitin-dependent proteostasis, the kit provides a dependable means to measure endogenous RAD23B concentrations in experimental samples.