Human PYCR2 ELISA Kit (HUFI06945)

The PYCR2 (pyrroline-5-carboxylate reductase 2) protein is a mitochondrial enzyme that catalyzes the final step of proline biosynthesis, converting pyrroline-5-carboxylate into L-proline. This Assay Genie ELISA kit enables quantitative measurement of PYCR2 in human samples, supporting research into proline metabolism, mitochondrial function, and connective tissue biology. Loss-of-function mutations in the PYCR2 gene are linked to autosomal recessive cutis laxa, hypomyelination, and neurodevelopmental disorders, making this assay valuable for studies of proline cycle dysfunction, oxidative stress responses, and pediatric neurological disease models. The microplate-based workflow supplies all necessary reagents in a single kit, and the standard protocol is compatible with common laboratory ELISA readers used in academic and translational research environments.