Human PUS1 ELISA Kit (HUFI06961)

Pseudouridine synthase 1 (PUS1) is the enzyme responsible for catalyzing the isomerization of uridine to pseudouridine, the most abundant post-transcriptional RNA modification found in tRNAs, rRNAs, and snRNAs. This Human PUS1 ELISA Kit from Assay Genie provides a research-use-only immunoassay for quantifying PUS1 levels in human-derived samples, supporting studies of RNA modification biology, mitochondrial translation, and conditions such as MLASA1, a rare autosomal recessive disorder linked to PUS1 loss-of-function mutations and characterized by myopathy, lactic acidosis, and sideroblastic anemia. The kit is supplied in a microplate format containing all reagents required to complete the assay workflow, and the plate-reader-compatible readout allows standard quantification without specialized instrumentation.