Human PTPN5 ELISA Kit (HUFI06970)

The PTPN5 target, also known as STEP (Striatal-Enriched protein tyrosine Phosphatase), is a brain-enriched non-receptor tyrosine phosphatase that regulates NMDA receptor trafficking, ERK/MAPK signaling, and synaptic plasticity in central nervous system neurons. Dysregulated STEP activity has been implicated in Alzheimer's disease, Parkinson's disease, schizophrenia, and fragile X syndrome, so quantitative PTPN5 measurement supports neurodegeneration and neuropharmacology research.

This Assay Genie sandwich ELISA kit is configured for 96 Assays on a microplate and validated for human serum and plasma. A human-specific capture antibody is paired with a biotinylated detection antibody and streptavidin-HRP for signal generation, supporting selective quantification of PTPN5 in neuronal and peripheral tissue lysates. Reconstituted standards and diluted samples should be aliquoted to limit freeze-thaw cycles, and the kit components require refrigerated storage with protection from light to preserve immunoreactivity.