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Human PTPN11 (Tyrosine-protein phosphatase non-receptor type 11) ELISA Kit (HUFI06968)
  • Human PTPN11 (Tyrosine-protein phosphatase non-receptor type 11) ELISA Kit (HUFI06968)
Assay Genie

Human PTPN11 (Tyrosine-protein phosphatase non-receptor type 11) ELISA Kit (HUFI06968)

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HUFI06968

Price on request

Description

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Built for quantitative measurement of human PTPN11, this ELISA kit from Assay Genie delivers a 96 Assays format aimed at laboratories researching the SHP-2 phosphatase and its role in cellular signaling. PTPN11 encodes SHP-2, a cytoplasmic non-receptor tyrosine phosphatase that couples growth factor, cytokine, and integrin inputs to the Ras/MAPK and PI3K/AKT cascades; pathogenic variants in this gene are linked to Noonan syndrome, LEOPARD syndrome, and certain hematologic malignancies. The kit supports signal transduction studies, mutation-effect analyses, and pathway activity profiling in research use only workflows. Reagents are organized to enable standard curve generation and direct sample quantification within a standard microplate format. Colorimetric readout is performed on a conventional plate reader, and each kit includes sufficient components for the full 96 Assays batch.