Human PTCH1 ELISA Kit (HUFI06979)

The PTCH1 protein (Patched-1) operates as the transmembrane receptor for the Hedgehog signaling pathway, normally restraining Smoothened activation until bound by Sonic, Indian, or Desert Hedgehog ligands. Mutations, epigenetic silencing, and dysregulated expression of PTCH1 are strongly linked to basal cell carcinoma, medulloblastoma, rhabdomyosarcoma, and Gorlin syndrome, positioning PTCH1 quantification as a recurring tool in oncology, developmental biology, and regenerative medicine research.

The Assay Genie kit uses a human-specific capture antibody pair, delivering absorbance-based readout across one microplate run per kit. Reconstituted standards should be aliquoted and stored frozen to limit freeze-thaw cycles, with unopened components kept refrigerated and intended for research use only, in vitro applications.