Human PSPH ELISA Kit (HUFI06987)

Phosphoserine Phosphatase (PSPH) is the terminal enzyme of the L-serine biosynthesis pathway, hydrolyzing O-phosphoserine to L-serine, and the Assay Genie Human PSPH ELISA Kit provides an in vitro research immunoassay for quantitative detection of PSPH in human-derived samples. PSPH has attracted research interest in neurobiology because L-serine feeds D-serine, glycine, and phospholipid biosynthesis, and altered PSPH expression has been reported in studies of brain development, neurodegenerative disease models, and tumor cell lines that rely on de novo serine synthesis. The assay is intended for research use only and is supplied as a complete kit containing pre-coated microplate wells, calibrated standards, detection reagents, and buffers required to run the full protocol. Standard laboratory absorbance plate readers capture the readout, making the workflow compatible with common immunology and cell biology laboratories. Applications include profiling PSPH expression in normal and disease-state samples, screening compounds that modulate serine metabolism, and supporting studies of the serine-glycine one-carbon metabolism axis in oncology and neuroscience research programs.