Human Proteinase-activated receptor 4 (F2RL3) ELISA Kit

This Sandwich ELISA Kit from Assay Genie is intended for the quantitative measurement of human Proteinase-activated receptor 4 (F2RL3) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Detection is colorimetric and the assay is validated for human samples.

Proteinase-activated receptor 4 (also known as coagulation factor II receptor-like 3, thrombin receptor-like 3, PAR-4 or PAR4) is a G-protein coupled receptor activated by thrombin or trypsin that stimulates phosphoinositide hydrolysis and contributes to platelet activation. Dysregulation of this receptor has been associated with cancer, cardiovascular disease and inflammation-related disorders, making it a relevant target for research.

Manufacturer-reported performance figures include a detection range of 0.78-50ng/mL, a sensitivity of 0.23ng/mL, an intra-assay CV of 4.9% and an inter-assay CV of 8.7%. Specificity covers natural and recombinant human Proteinase-activated receptor 4. Recovery is reported at 91-103% in serum and 93-105% in plasma. For research use only.