Human Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) ELISA Kit

PPP2R4 encodes the phosphotyrosyl phosphatase activator (PTPA), a peptidyl-prolyl cis-trans isomerase that binds the serine/threonine phosphatase PP2A and stimulates its activity in an ATP-dependent manner. Quantitative measurement of regulatory subunit expression in human tissue homogenates supports studies of cell cycle control, apoptosis regulation, and PP2A tumor suppressor signaling, with particular relevance for Alzheimer's disease research, where reduced PTPA activity has been linked to tau hyperphosphorylation.

The complete assay workflow runs in approximately 3.5 hours, allowing researchers to integrate target measurement into existing western blot or immunohistochemistry pipelines. Each kit from Assay Genie includes a pre-coated microplate, calibrated standards, biotinylated detection antibody, and assay diluent sufficient for the full run.