Human Protein notum homolog (NOTUM) ELISA Kit

From Assay Genie, this Sandwich ELISA kit is designed for the quantitative measurement of NOTUM (Notum Homolog) levels in human samples, with stated applicability to serum, plasma, and cell culture supernatants. The target is also known by the synonyms hNOTUM and OK/SW-CL.30, and the assay uses an ELISA-based detection method with human reactivity.

Reported performance specifications include a detection range of 78-5000pg/mL and a sensitivity of 33pg/mL, with an intra-assay CV of 5.4% and inter-assay CV of 9.5%. Specificity is described for natural and recombinant human Palmitoleoyl-protein carboxylesterase NOTUM. NOTUM is described as a carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleylation of WNT proteins, and has been implicated in diseases such as cancer and developmental disorders. The protein is classified under the research area of Neurosciences with a subcellular location of Secreted, and is associated with UniProt entry Q6P988 at a molecular weight of 55,699 Da.

The product is intended for research use only.